BCOR-CCNB3 rearranged sarcoma arising in neck misdiagnosed as thyroid cancer: A case report. (September 2021)

• Record Type: Journal Article
• Authors: Tan, Li-Cheng; Yu, Peng-Cheng; Wang, Jian; Zhou, Xiao-Yan; Ji, Qing-Hai; Wang, Yu-Long
• Is Part Of: Oral oncology. Volume 120(2021)
• Publication Date: 2021-09
• Subjects: Undifferentiated round cell sarcoma -- BCOR-rearrangement -- Thyroid; Mouth -- Cancer -- Periodicals; Mouth -- Tumors -- Periodicals; Mouth Diseases -- Periodicals; Mouth Neoplasms -- Periodicals; Bouche -- Cancer -- Périodiques; Bouche -- Tumeurs -- Périodiques; Tumeurs -- Périodiques; Electronic journals; 616.9943105
• DOI: 10.1016/j.oraloncology.2021.105290
• Languages: English
• ISSNs: 1368-8375

Abstract

Abstract: BCOR -rearranged sarcoma is the third common subtype of undifferentiated small round cell sarcoma and was first recognized in 2012 from bone sarcoma with a similar morphological manifestation with undifferentiated round cell but totally different molecular hallmark from Ewing sarcoma. Primary BCOR -rearranged sarcomas were mostly found in bone and soft tissue and were sporadically reported in viscera involving kidney, which add difficulties in differential diagnosis. Here we present a 21 years old male patient with BCOR-CCNB3 in neck, which first diagnosed as thyroid cancer.