Absence of SARS-CoV-2 antibodies in pre-pandemic plasma from children and adults in Vietnam. (October 2021)

• Record Type: Journal Article
• Authors: Chau, Nguyen Van Vinh; Nhan, Le Nguyen Thanh; Nguyet, Lam Anh; Tu, Nguyen Thi Kha; Hong, Nguyen Thi Thu; Man, Dinh Nguyen Huy; Ty, Dinh Thi Bich; Nhu, Le Nguyen Truc; Yen, Lam Minh; Khanh, Truong Huu; Quy, Du Tuan; Minh, Ngo Ngoc Quang; Ny, Nguyen Thi Han; Anderson, Danielle; Wang, Lin-Fa; van Doorn, H. Rogier; Hung, Nguyen Thanh; Thanh, Tran Tan; Thwaites, Guy; Tan, Le Van
• Is Part Of: International journal of infectious diseases. Volume 111(2021)
• Page Start: 127
• Page End: 129
• Publication Date: 2021-10
• Subjects: Cross-reactivity -- SARS-CoV-2 -- zoonosis -- COVID-19; Communicable diseases -- Periodicals; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; Electronic journals; 616.9
• DOI: 10.1016/j.ijid.2021.07.072
• Languages: English
• ISSNs: 1201-9712

Abstract

Abstract: We tested pre-pandemic (2015–-2019) plasma samples from 148 Vietnamese children and 100 Vietnamese adults at high risk of zoonotic infections for antibodies against SARS-CoV-2 nucleocapsid and spike proteins. None was positive. The data thus demonstrated no evidence of prior serological cross-reactivity with SARS-CoV-2 that might explain the low numbers of COVID-19 in Vietnam. No pre-existing cross-reactivity might explain Vietnam success of COVID-19 control.