Subcutaneous ertapenem delivered by an Australian outpatient parenteral antimicrobial therapy service: a retrospective comparative efficacy study. Issue 10 (18th October 2021)

• Record Type: Journal Article
• Authors: Hiew, Jonathan; Whitmore, Timothy; McEvoy, Mahalia; Weatherall, Deborah; Ingram, Paul R.; Manning, Laurens
• Is Part Of: Internal medicine journal. Volume 51:Issue 10(2021)
• Page Start: 1717
• Page End: 1721
• Publication Date: 2021-10-18
• Subjects: subcutaneous -- ertapenem -- outpatient parenteral antimicrobial therapy; Medicine -- Periodicals; 616
• DOI: 10.1111/imj.15511
• Languages: English
• ISSNs: 1444-0903

Abstract

Abstract: Subcutaneous (SC) administration of ertapenem in outpatient parenteral antimicrobial therapy (OPAT) services may be a practical alternative to intravenous delivery for complicated infections. The clinical features and outcomes according to route of administration were compared from a large Australian OPAT service. Chronic renal impairment was more common in the SC group, reflecting an opportunity for route of administration as a vein preservation strategy. Adverse events were uncommon and successful outcomes were not different between the groups.