Suppurative keloids: a complication of severe keloid disease. (11th May 2021)

• Record Type: Journal Article
• Authors: Delaleu, Jeremie; Duverger, Lucie; Shourick, Jason; Tirgan, Michael H.; Algain, Maysoon; Tounkara, Thierno; Kourouma, Sarah; Bagot, Martine; Petit, Antoine
• Is Part Of: International journal of dermatology. Volume 60:Number 11(2021)
• Page Start: 1392
• Page End: 1396
• Publication Date: 2021-05-11
• Subjects: Dermatology -- Periodicals; 616.5
• DOI: 10.1111/ijd.15641
• Languages: English
• ISSNs: 0011-9059

Abstract

Abstract: Background: Some keloids show cystic cavities that give rise to acute inflammatory flares and oozing. These suppurative keloids (SK) have rarely been systematically studied. We conducted a retrospective cohort study to evaluate SK frequency and its risk factors. We also reviewed microbiological analyses as well as the histological features of removed SKs. Methods: Between July 1, 2015, and September 30, 2016, all adult patients attending a specialized keloid clinic were asked to participate. Clinical information and microbiological results were extracted from each patient's file. Histological features were observed and interpreted. Results: In this study, we observed an SK rate of 26% for a mean keloid history of 17.2 years. Male gender, African ancestry, and a family history of keloids were significantly associated with suppuration. Microbiological examination revealed commensal skin flora 7/9 (77.8%), Staphylococcus aureus 1/9 (11.1%), and Enterococcus faecalis 1/9 (11.1%). Conclusion: Suppuration is a common complication of keloids occurring in patients with severe keloid disease and may arise from pilosebaceous occlusion and aseptic inflammation.