Dynamic brain connectome and high risk of mental problem in clinical nurses. Issue 16 (31st July 2021)

• Record Type: Journal Article
• Authors: Bai, Ling; JI, Gong‐Jun; Song, Yongxia; Sun, Jinmei; Wei, Junjie; Xue, Fang; Zhu, Lu; Li, Rui; Han, Yanfang; Zhang, Liu; Yang, Jinying; Qiu, Bensheng; Wu, Guo‐Rong; Zhang, Jing; Hong, Jingfang; Wang, Kai; Zhu, Chunyan
• Is Part Of: Human brain mapping. Volume 42:Issue 16(2021)
• Page Start: 5300
• Page End: 5308
• Publication Date: 2021-07-31
• Subjects: dynamic -- functional connectivity -- mental health -- nurse; Brain mapping -- Periodicals; 611.81
• DOI: 10.1002/hbm.25617
• Languages: English
• ISSNs: 1065-9471

Abstract

Abstract: With the growing population and rapid change in the social environment, nurses in China are suffering from high rates of stress; however, the neural mechanism underlying this occupation related stress is largely unknown. In this study, mental status was determined for 81 nurses and 61 controls using the Symptom Checklist 90 (SCL‐90) scale. A subgroup ( n = 57) was further scanned by resting‐state functional MRI with two sessions. Based on the SCL‐90 scale, "somatic complaints" and "diet/sleeping" exhibited the most prominent difference between nurses and controls. This mental health change in nurses was further supported by the spatial independent component analysis on functional MRI data. First, dynamic functional connectome analysis identified two discrete connectivity configurations (States I and II). Controls had more time in the State I than II, while the nurses had more time in the State II than I. Second, nurses showed a similar static network topology as controls, but altered dynamic properties. Third, the symptom‐imaging correlation analysis suggested the functional alterations in nurses as potential imaging biomarkers indicating a high risk for "diet/sleeping" problems. In summary, this study emphasized the high risk of mental deficits in nurses and explored the underlying neural mechanism using dynamic brain connectome, which provided valuable information for future psychological intervention. Abstract : Nurses showed a high risk of mental problems in "somatic complaints" and "diet/sleeping." The proportion of different mental states was distinct between nurses and controls. The dynamic brain features were correlated with "diet/sleeping" symptoms.