Design, synthesis, and herbicidal activity of novel pyrimidine derivatives containing 1, 2, 4-triazole. (3rd October 2021)

• Record Type: Journal Article
• Authors: Zhu, Jiajun; He, Linghui; Luo, Jin; Xiong, Jun; Wang, Tao
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 196:Number 10(2021)
• Page Start: 948
• Page End: 953
• Publication Date: 2021-10-03
• Subjects: Pyrimidine derivatives containing 1, 2, 4-triazole -- synthesis -- preliminary herbicidal test -- inhibition activities; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2021.1946063
• Languages: English
• ISSNs: 1042-6507

Abstract

Abstract: A facile approach for the synthesis of pyrimidine derivatives containing 1, 2, 4-triazole moiety via the reaction of substituted 2-phenoxypropane hydrazide with ethyl- N -(5-cyano-2-alkylthio-5-cyano-6-methylthiopyrimidin-4-yl) formimidate in refluxing 2-methoxyethanol is reported. The structures of the title compounds were identified by 1 H NMR, 13 C NMR, and HRMS. The configuration of compound 5a was confirmed by X-ray crystallography analysis. The preliminary herbicidal test indicated that some of the target compounds exhibited good inhibition activities against Brassica napus (rape) and Echinochloa crusgalli (barnyard grass). GRAPHICAL ABSTRACT: UF0001