Image artefacts in swept-source optical coherence tomography angiography. Issue 5 (20th July 2016)

• Record Type: Journal Article
• Authors: Ghasemi Falavarjani, Khalil; Al-Sheikh, Mayss; Akil, Handan; Sadda, Srinivas R
• Is Part Of: British journal of ophthalmology. Volume 101:Issue 5(2017)
• Page Start: 564
• Page End: 568
• Publication Date: 2016-07-20
• Subjects: Imaging -- Retina; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjophthalmol-2016-309104
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Purpose: To describe optical coherence tomography angiography (OCTA) image artefacts in eyes with and without ocular pathologies. Methods: The OCTA images of healthy subjects and patients with age-related macular degeneration, diabetic retinopathy and retinal vascular occlusions were retrospectively reviewed. All OCTA images were obtained using a swept-source OCTA instrument (Triton, Topcon). The frequency of various image artefacts including segmentation, banding, motion, projection, masking, unmasking, doubling of the retinal vessels, blink, stretching, out-of-window and crisscross artefacts was assessed. The impact of the artefact on the grading of the images for the foveal avascular zone in deep and superficial retinal layers, capillary non-perfusion and choroidal neovascularisation (CNV) was evaluated. Results: OCTA images of 57 eyes of 48 subjects including 23 eyes (40.3%) with CNV, 13 eyes (22.8%) with dry age-related macular degeneration, 9 eyes (15.7%) with cystoid macular oedema due to diabetic retinopathy or retinal vein occlusion and 12 normal eyes (21.1%) were available for evaluation. At least one type of artefact was present in the images from 51 eyes (89.4%). Banding artefact, segmentation, motion, unmasking, blink, vessel doubling, masking and out-of-window artefacts were found in 51 (89.4%), 35 (61.4%), 28 (49.1%), 9 (15.8%), 5 (8.8%), 1 (1.7%), 1 eye (1.7%) and 1 eye (1.7%), respectively. Projection artefact, stretch artefact or crisscross artefact was not observed. Banding, motion and segmentation artefacts were statistically significantly more frequent in eyes with ocular pathology compared with control eyes (all p<0.001). Eyes with choroidal diseases had significantly higher rate of segmentation error in the choriocapillaris slab compared with eyes with only retinal disease (p=0.02). In nine eyes (17.6%), the artefacts were deemed severe enough by the graders to preclude accurate grading of the image. Conclusions: Image artefacts occur frequently in OCTA images. The artefacts are more frequent in eyes with pathology.