Circulating immune complexes in syphilitic nephropathy. A case report. Issue 1 (February 1978)

• Record Type: Journal Article
• Authors: Sølling, J; Sølling, K; Jacobsen, K U; Olsen, S; From, E
• Is Part Of: Sexually transmitted infections. Volume 54:Issue 1(1978)
• Page Start: 53
• Page End: 56
• Publication Date: 1978-02
• Subjects: Sexually transmitted diseases -- Periodicals; HIV infections -- Periodicals; 616.951005
• DOI: 10.1136/sti.54.1.53
• Languages: English
• ISSNs: 1368-4973

Abstract

Abstract : A case of transient nephrotic syndrome caused by secondary syphilis is described. A renal biopsy was performed revealing subepithelial hump-like electron-dense deposits and fusion of epithelial foot-processes. Complement C1q-binding-activity and anticomplementarity were demonstrated in the blood, indicating the presence of circulating immune complexes. This strongly suggests that circulating immune complexes are significant in the immunopathogenesis of syphilitic nephropathy.