In-vitro antigonococcal activity of rosoxacin (WIN 35213). Issue 1 (February 1981)

• Record Type: Journal Article
• Authors: Warren, C A; Shannon, K P; Phillips, I
• Is Part Of: Sexually transmitted infections. Volume 57:Issue 1(1981)
• Page Start: 33
• Page End: 35
• Publication Date: 1981-02
• Subjects: Sexually transmitted diseases -- Periodicals; HIV infections -- Periodicals; 616.951005
• DOI: 10.1136/sti.57.1.33
• Languages: English
• ISSNs: 1368-4973

Abstract

Abstract : The in-vitro activity of rosoxacin against 173 isolates of Neisseria gonorrhoeae, including 17 beta-lactamase-producers, was tested by an agar dilution method. Of the isolates, 167 (including 16 of the beta-lactamase-producers) were inhibited by 0 . 06 mg/l of rosoxacin. The remaining six isolates, one of which produced beta-lactamase and the others were moderately resistant to penicillin, were inhibited by 0 . 12-0 25 mg/l of the compound. There was little correlation between the minimum inhibitory concentrations (MICs) of rosoxacin and penicillin, except for isolates with MICs of penicillin of 0 . 06-1 mg/l, for which correlation was good.