Vasculitis complicating treatment with intravenous anisoylated plasminogen streptokinase activator complex in acute myocardial infarction. Issue 1 (January 1988)

• Record Type: Journal Article
• Authors: Bucknall, C; Darley, C; Flax, J; Vincent, R; Chamberlain, D
• Is Part Of: Heart. Volume 59:Issue 1(1988)
• Page Start: 9
• Page End: 11
• Publication Date: 1988-01
• Subjects: Heart -- Diseases -- Treatment -- Periodicals; Cardiology -- Periodicals; 616.12
• DOI: 10.1136/hrt.59.1.9
• Languages: English
• ISSNs: 1355-6037

Abstract

Abstract : Vasculitis developed in six of 253 patients treated with intravenous anisoylated plasminogen streptokinase activator complex (APSAC) after acute myocardial infarction. All patients recovered spontaneously with no evidence of renal impairment and no long term sequelae. Although leucocytoclastic vasculitis and serum sickness have been reported after streptokinase treatment, such allergic reactions have not been described as a complication of other thrombolytic agents.