Translocation 21q22q in an infertile human male. Issue 5 (October 1982)

• Record Type: Journal Article
• Authors: Chandley, A C; Hargreave, T B; Fletcher, J M
• Is Part Of: Journal of medical genetics. Volume 19:Issue 5(1982)
• Page Start: 366
• Page End: 369
• Publication Date: 1982-10
• Subjects: Medical genetics -- Periodicals; 616.042
• DOI: 10.1136/jmg.19.5.366
• Languages: English
• ISSNs: 1468-6244

Abstract

Abstract : Details are given of a balanced 21q22q Robertsonian translocation ascertained through infertility in a phenotypically normal male. Chromosome analyses on the proband and his parents showed that the translocation arose as a new mutation. The patient was oligospermic and had a high frequency of morphological abnormalities in his spermatozoa. Meiotic investigations showed a chain trivalent in all primary spermatocytes examined at diakinesis/metaphase I. The testicular histology was normal.