Implications of breast cancer with diabetes mellitus on patient outcomes and care. (September 2014)

• Record Type: Journal Article
• Authors: Karlin, Nina J; Dueck, Amylou C; Nagi Reddy, Sravan K; Verona, Patricia M; Cook, Curtiss B
• Is Part Of: Diabetes management. Volume 4:Number 5(2014)
• Page Start: 411
• Page End: 419
• Publication Date: 2014-09
• Subjects: breast cancer -- diabetes mellitus -- glycemic control -- outcome -- survival; Diabetes -- Periodicals; 616.462005
• DOI: 10.2217/dmt.14.39
• Languages: English
• ISSNs: 1758-1915

Abstract

SUMMARY : Aims: The aim of this study was to determine the impact of diabetes mellitus (DM) on short-term overall survival and time to recurrence (TTR) in breast cancer patients, and examine the impact of breast cancer on glycemic control in DM.Methods: From a data set of newly diagnosed breast cancer patients (2007–2011), we identified 109 patients with DM and 109 matched controls.Results: Hemoglobin A1c among cases did not significantly change over 1 year (p = 0.10). Cases and controls showed no differences in OS (hazard ratio: 1.25; 95% CI: 0.49–3.17) during the median follow-up of 2.2 years (range: 0.1–4.9 years) and no differences in TTR (hazard ratio: 1.00; 95% CI: 0.14–7.10).Conclusion: DM did not adversely affect metabolic control, short-term OS or TTR.