Blood HCO3- concentration predicts the long-term prognosis of acute kidney injury patients. (December 2014)

• Record Type: Journal Article
• Authors: Che, Xiajing; Xie, Yuanyuan; Wang, Chunlin; Wang, Qin; Zhang, Minfang; Qi, Chaojun; Ni, Zhaohui; Mou, Shan
• Is Part Of: Biomarkers in medicine. Volume 8:Number 10(2014)
• Page Start: 1219
• Page End: 1226
• Publication Date: 2014-12
• Subjects: acute kidney injury (AKI) -- blood HCO3- concentration -- combined markers -- Cox regression analysis -- follow-up -- Kaplan–Meier method -- prevention -- receiver operating characteristic–area under the curve -- renal prognosis; Biochemical markers -- Periodicals; 610.28
• DOI: 10.2217/bmm.14.91
• Languages: English
• ISSNs: 1752-0363

Abstract

Aim: To evaluate the value of HCO3 - concentrations in long-term prognosis after acute kidney injury.Patients & methods: A total of 169 AKI patients were included in this study. At the 12‐month follow-up, the patients were divided into recovered and unrecovered groups.Results: The blood HCO3 - concentrations were significantly correlated with poor prognosis. The area under the curve for renal prognosis of 6 months later blood HCO3 - concentrations was 0.798. Combined HCO3 - and Scr level area under the curve was 0.952.Conclusion: The blood HCO3 - level was useful in evaluating renal prognosis of acute kidney injury patients. The combination of blood HCO3 - concentration and Scr level increased the accuracy of prediction.