Cover Feature: Substrate‐Controlled Cyclopropanation Reactions of Glycals with Aryl Diazoacetates (ChemCatChem 16/2020). Issue 16 (21st August 2020)

• Record Type: Journal Article
• Authors: Guo, Yujing; Pei, Chao; Koenigs, Rene M.
• Is Part Of: ChemCatChem. Volume 12:Issue 16(2020)
• Page Start: 3957
• Page End: 3957
• Publication Date: 2020-08-21
• Subjects: diazoalkane -- carbene -- cyclopropanation -- sugar; Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.202001194
• Languages: English
• ISSNs: 1867-3880

Abstract

Abstract : The Cover Feature shows an achiral rhodium(II) complex that undergoes formation of rhodium donor/acceptor carbene complexes. This rhodium complex can react in a stereoselective cyclopropanation reaction with glucal derivatives giving two different cyclopropane products depending on the acceptor group of the carbene. In their Communication, Y. Guo et al. describe the application of this cyclopropanation with a broad range of different glucal derivatives and donor/acceptor diazoalkanes. Theoretical calculations are then used to rationalize for the distinct reactivity of aryldiazoacetates vs. trifluoromethylated donor/acceptor diazoalkanes to provide an understanding of the different pathways in this cyclopropanation reaction. More information can be found in the Communication by Y. Guo et al.