Severe antibody‐mediated transfusion‐related acute lung injury in an obstetric patient following transfusion of fresh frozen plasma from a non‐transfused male blood donor. Issue 6 (10th June 2021)

• Record Type: Journal Article
• Authors: Agergaard, Charlotte Nielsen; Haunstrup, Thure Mors; Fjordside, Anne‐Louise; Baech, John; Steffensen, Rudi; Nielsen, Kaspar René
• Is Part Of: Clinical case reports. Volume 9:Issue 6(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-06-10
• Subjects: neutrophil antibodies -- plasma -- TRALI -- Transfusion; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.3818
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Transfusion‐Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life‐threatening TRALI in an obstetric patient triggered by transfusion from a non‐transfused male blood donor. A residual risk of TRALI exist, even in a male‐only plasma setting. Abstract : Transfusion‐Related Acute Lung Injury (TRALI) has been associated with neutrophil reacting antibodies in transfused blood products. We report a case of life‐threatening TRALI in an obstetric patient triggered by transfusion from a non‐transfused male blood donor. A residual risk of TRALI exist, even in a male‐only plasma setting.