Determination of Particle Size, Core and Shell Size Distributions of Core–Shell Particles by Analytical Ultracentrifugation. (26th August 2021)

• Record Type: Journal Article
• Authors: Schmidt, Thomas; Linders, Jürgen; Mayer, Christian; Cölfen, Helmut
• Is Part Of: Particle and particle systems characterization. Volume 38:Number 10(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-08-26
• Subjects: analytical ultracentrifugation -- core–shell particles -- density matching -- particle density distribution -- particle size distribution; Particles -- Periodicals; 620.43
• DOI: 10.1002/ppsc.202100079
• Languages: English
• ISSNs: 0934-0866

Abstract

Abstract: In core–shell nanoparticle analysis, the determination of size distributions of the different particle parts is often complicated, especially in liquid media. Density matching is introduced as a method for analyzing core–shell nanoparticles using Analytical Ultracentrifugation (AUC), making it possible to obtain the core size distribution in liquid dispersions. For this approach, the density of the dispersion is adjusted to the density of the shell. Oil filled nanocapsules are utilized with component densities of around 1 g mL −1 to demonstrate this technique. The shell size distribution is calculated supposing the particle size distribution as a convolution of the shell‐ and core size distributions. Finally, the distributions of core size, shell thickness, particle size, and particle density and thus particle composition are obtained. To clarify the effect of swelling, AUC measurements are combined with further size characterization methods like Particle Tracking Microscopy and Dynamic Light Scattering. Abstract : Density matching, a new method for analytical ultracentrifugation, yields the distribution of core size, shell thickness, particle size/density, and composition of core–shell nanoparticles in liquid media. The method is facile to realize by readily adjusting the density of the medium.