Trimethoprim and Sulphamethoxazole in Typhoid. Issue 5620 (21st September 1968)

• Record Type: Journal Article
• Authors: Akinkugbe, O. O.; Lewis, E. A.; Montefiore, D.; Okubadejo, O. A.
• Is Part Of: BMJ. Volume 3:Issue 5620(1968)
• Page Start: 721
• Page End: 722
• Publication Date: 1968-09-21
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.3.5620.721
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : Six patients with proved typhoid fever were treated with a combination of trimethoprim and sulphamethoxazole; four others were treated with chloramphenicol. All ten patients made an uneventful recovery. Though the numbers are small it appears that the patients treated with the combined drugs did just as well as those treated with chloramphenicol, and fever seemed to subside quicker with the combined drugs. Trimethoprim and sulphamethoxazole have low toxicities, so further studies of their use in the treatment of typhoid are justified.