Relation between Airways Obstruction and CO2 Tension in Chronic Obstructive Airways Disease. Issue 5620 (21st September 1968)

• Record Type: Journal Article
• Authors: Lane, D. J.; Howell, J. B. L.; Giblin, B.
• Is Part Of: BMJ. Volume 3:Issue 5620(1968)
• Page Start: 707
• Page End: 709
• Publication Date: 1968-09-21
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.3.5620.707
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The relationship between the F.E.V.1 as an index of airways obstruction and Pco2 as an index of hypoventilation was investigated in 13 patients with chronic obstructive airways disease. Patients who had a normal Pco2 despite severe airways obstruction retained relatively normal sensitivity to CO2 as assessed by their "inspiratory mechanical work rate" response to CO2 . Others showed a raised Pco2 in the presence of lesser degrees of airways obstruction and had reduced sensitivity to CO2 .