Serum albumin concentration, arm circumference, and oedema and subsequent risk of dying in children in central Africa. Issue 6906 (18th September 1993)

• Record Type: Journal Article
• Authors: Dramaix, M; Hennart, P; Brasseur, D; Bahwere, P; Mudjene, O; Tonglet, R; Donnen, P; Smets, R
• Is Part Of: BMJ. Volume 307:Issue 6906(1993)
• Page Start: 710
• Page End: 713
• Publication Date: 1993-09-18
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.307.6906.710
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : OBJECTIVE--To measure the prognostic value of clinical, anthropometric, and biological indicators of protein energy malnutrition in hospitalised children. DESIGN--Hospital based follow up study from admission to discharge or death of a cohort of children. SETTING-Paediatric hospital in Zaire. SUBJECTS--1129 children consecutively admitted between August 1986 and October 1988. MAIN OUTCOME MEASURES--Height, weight, arm circumference, skinfold thicknesses, serum albumin concentration, and mortality. RESULTS--Mortality was higher in wasted children and in those with a mid-upper arm circumference < 125 mm, a serum albumin concentration < 16 g/l, and oedema. After multivariate analysis, serum albumin concentration was the best predictor of subsequent risk of dying. Mid-upper arm circumference and oedema, however, still contributed considerably to evaluation of mortality. CONCLUSIONS--In this specific environment of central Africa an isolated clinical sign such as oedema is not enough to detect children with a high risk of dying among those admitted to paediatric wards with severe protein energy malnutrition. Measurement of additional indicators such as arm circumference and serum albumin concentration seems to be of crucial importance.