Feasibility of using the Vero SBRT system for intracranial SRS. (6th January 2014)

• Record Type: Journal Article
• Authors: Burghelea, Manuela; Verellen, Dirk; Gevaert, Thierry; Depuydt, Tom; Poels, Kenneth; Simon, Viorica; Ridder, Mark De
• Is Part Of: Journal of applied clinical medical physics. Volume 15:Number 1(2014)
• Page Start: 90
• Page End: 99
• Publication Date: 2014-01-06
• Subjects: O‐ring gantry -- treatment planning -- intracranial radiosurgery; Medical physics -- Periodicals; Clinical medicine -- Periodicals; Health Physics; Clinical Medicine; Electronic journals; Periodicals; Periodicals; Fulltext; Internet Resources; 610.153
• DOI: 10.1120/jacmp.v15i1.4437
• Languages: English
• ISSNs: 1526-9914

Abstract

Abstract : The Vero SBRT system was benchmarked in a planning study against the Novalis SRS system for quality of delivered dose distributions to intracranial lesions and assessing the Vero system's capacity for SRS. A total of 27 patients with one brain lesion treated on the Novalis system, with 3 mm leaf width MLC and C‐arm gantry, were replanned for Vero, with a 5 mm leaf width MLC mounted on an O‐ring gantry allowing rotations around both the horizontal and vertical axis. The Novalis dynamic conformal arc (DCA) planning included vertex arcs, using 90° couch rotation. These vertex arcs cannot be reproduced with Vero due to the mechanical limitations of the O‐ring gantry. Alternative class solutions were investigated for the Vero. Additionally, to distinguish between the effect of MLC leaf width and different beam arrangements on dose distributions, the Vero class solutions were also applied for Novalis. In addition, the added value of noncoplanar IMRT was investigated in this study. Quality of the achieved dose distributions was expressed in the conformity index (CI) and gradient index (GI), and compared using a paired Student's t‐test with statistical significance for p‐values ≤ 0.05 . For lesions larger than 5 cm 3, no statistical significant difference in conformity was observed between Vero and Novalis, but for smaller lesions, the dose distributions showed a significantly better conformity for the Novalis ( Δ C I = 13.74 %, p = 0.0002 ) mainly due to the smaller MLC leaf width. Using IMRT on Vero reduces this conformity difference to nonsignificant levels. The cutoff for achieving a GI around 3, characterizing a sharp dose falloff outside the target volume was 4 cm 3 for Novalis and 7 cm 3 for Vero using DCA technique. Using noncoplanar IMRT, this threshold was reduced to 3 cm 3 for the Vero system. The smaller MLC and the presence of the vertex fields allow the Novalis system to better conform the dose around the lesion and to obtain steeper dose falloff outside the lesion. Comparable dosimetric characteristics can be achieved with Vero for lesions larger than 3 cm 3 and using IMRT. PACS number: 87.55.D