Development and Characterization of Electrospun Poly(2‐hydroxy ethyl methacrylate) for Tissue Engineering Applications. Issue 3 (1st August 2013)

• Record Type: Journal Article
• Authors: Ramalingam, Nithya; Natarajan, Thirupathur Srinivasan; Rajiv, Sheeja
• Is Part Of: Advances in polymer technology. Volume 32:Issue 3(2013:Autumn)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2013-08-01
• Subjects: Biological applications of polymers -- Electrospinning -- Fibers -- Nanotechnology -- pHEMA; Plastics -- Periodicals; Polymers -- Periodicals; 668.9
• DOI: 10.1002/adv.21348
• Languages: English
• ISSNs: 0730-6679

Abstract

ABSTRACT: Electrospinning is a reliable method to produce polymer nanofibers for medical applications. In this report, poly(2‐hydroxy ethyl methacrylate) (p(HEMA)) was electrospun using ethanol and water (4:1) to produce nanofibers. Electrospinning parameters such as the polymer concentration, flow rate, electric field, and distance between needle and collector were optimized. Nanofibers with diameters ranging from nano‐ to micrometer were obtained as seen through a scanning electron microscope. Solvent evaporation, thermal stability, crystallinity, storage modulus, and viscoelastic behavior were analyzed using FTIR, thermal analysis, X‐ray diffraction, and dynamical mechanical analysis respectively. This polymer fiber with mechanical strength, high swelling ratio, and good cell viability is shown to be an excellent biocompatible polymer for tissue engineering applications. © 2013 Wiley Periodicals, Inc. Adv Polym Technol 2013, 32, 21348; View this article online at wileyonlinelibrary.com . DOI 10.1002/adv.21348