ChemInform Abstract: Chemoselective Reductive Nucleophilic Addition to Tertiary Amides, Secondary Amides, and N‐Methoxyamides. Issue 22 (15th May 2015)

• Record Type: Journal Article
• Authors: Nakajima, Minami; Oda, Yukiko; Wada, Takamasa; Minamikawa, Ryo; Shirokane, Kenji; Sato, Takaaki; Chida, Noritaka
• Is Part Of: ChemInform. Volume 46:Issue 22(2015)
• Page Start: no
• Page End: no
• Publication Date: 2015-05-15
• Subjects: addition reactions -- chemoselective reactions -- amines (benzene compounds); Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201522028
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The title transformation consists of (i) reduction of the amide carbonyl group, (ii) formation of an iminium ion with an acid, and (iii) C—C bond formation with a mild nucleophile.