ChemInform Abstract: A Lewis Acid Activated Reaction of Zn with EtI to Promote Highly Enantioselective Alkyne Additions to Aldehydes. Issue 22 (15th May 2015)

• Record Type: Journal Article
• Authors: Chen, Shan‐yong; Liu, Winnie; Wu, Xuedan; Ying, Jun; Yu, Xiaoqi; Pu, Lin
• Is Part Of: ChemInform. Volume 46:Issue 22(2015)
• Page Start: no
• Page End: no
• Publication Date: 2015-05-15
• Subjects: alcohols (benzene compounds) -- alkynes (benzene compounds) -- alkynes (acyclic compounds) -- diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) -- addition reactions; Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201522088
• Languages: English
• ISSNs: 0931-7597

Abstract

Abstract: The reaction of Zn with EtI is activated at room temperature by using BINOL and Ti(OiPr)4 which can then promote the highly enantioselective alkyne addition to aromatic aldehydes.