Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling. Issue 2 (2015)

• Record Type: Journal Article
• Authors: Bell, Gillian C.; Padron, Eric
• Is Part Of: Leukemia research reports. Volume 4:Issue 2(2015)
• Page Start: 70
• Page End: 71
• Publication Date: 2015
• Subjects: Leukemia -- Periodicals; Lymphomas -- Periodicals; Multiple myeloma -- Periodicals; Leukemia -- Periodicals; Lymphoma -- Periodicals; Multiple Myeloma -- Periodicals; Hematologic Neoplasms -- Periodicals; Leukemia; Lymphomas; Multiple myeloma; Electronic journals; Periodicals; 616.9941905
• DOI: 10.1016/j.lrr.2015.07.002
• Languages: English
• ISSNs: 2213-0489

Abstract

Abstract: In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additional treatment options.