Socioeconomic Influences on Short-term Postoperative Outcomes in Patients With Oral Cavity Cancer Undergoing Free Flap Reconstruction. (February 2022)

• Record Type: Journal Article
• Authors: Lee, Jaclyn; Fernando, Shanik J.; Malenke, Jordan A.; Totten, Douglas J.; Kloosterman, Nicole; Langerman, Alexander; Kim, Young J.; Mannion, Kyle; Sinard, Robert; Netterville, James; Rohde, Sarah L.
• Is Part Of: Otolaryngology--head and neck surgery. Volume 166:Number 2(2022)
• Page Start: 274
• Page End: 281
• Publication Date: 2022-02
• Subjects: median household income -- area deprivation index -- head and neck cancer -- free flap outcomes -- oral cavity squamous cell carcinoma; Head -- Surgery -- Periodicals; Neck -- Surgery -- Periodicals; Otolaryngology -- Periodicals; 617.51
• DOI: 10.1177/01945998211012954
• Languages: English
• ISSNs: 0194-5998

Abstract

Objective: To evaluate the associations between median household income (MHI) and area deprivation index (ADI) on postoperative outcomes in oral cavity cancer. Study Design: Retrospective review (2000-2019). Setting: Single-institution tertiary medical center. Methods: MHI and ADI were matched from home zip codes. Main postoperative outcomes of interest were length of tracheostomy use, length of hospital stay, return to oral intake, discharge disposition, and 60-day readmissions. Linear and logistic regression controlled for age, sex, race, body mass index, tobacco and alcohol use history, primary tumor location, disease staging at presentation, and length of surgery. A secondary outcome was clinical disease staging (I-IV) at time of presentation. Results: The cohort (N = 681) was 91.3% White and 38.0% female, and 51.7% presented with stage IV disease. The median age at the time of surgery was 62 years (interquartile range [IQR], 53-71). The median MHI was $47, 659 (IQR, $39, 324-$58, 917), and the median ADI was 67 (IQR, 48-79). ADI and MHI were independently associated with time to return of oral intake (β = 0.130, P = .022; β = −0.092, P = .045, respectively). Neither was associated with length of tracheostomy, hospital stay, discharge disposition, or readmissions. MHI quartiles were associated with a lower risk of presenting with more advanced disease (Q3 vs Q1: adjusted odds ratio, 0.56 [95% CI, 0.32-0.97]). Conclusion: MHI is associated with oral cavity cancer staging at the time of presentation. MHI and ADI are independently associated with postoperative return to oral intake following intraoral tumor resection and free flap reconstruction.