Application of step and beat alignment approaches and its effect on gait in progressive multiple sclerosis with severe cerebellar ataxia: A proof of concept case study. (March 2022)

• Record Type: Journal Article
• Authors: Moumdjian, Lousin; Moens, Bart; Van Wijmeersh, Bart; Leman, Marc; Feys, Peter
• Is Part Of: Multiple sclerosis. Volume 28:Number 3(2022)
• Page Start: 492
• Page End: 495
• Publication Date: 2022-03
• Subjects: Multiple sclerosis -- gait -- adaptive alignment approach -- non-adaptive alignment approach -- synchronisation -- music -- −12% tempo; Central nervous system -- Diseases -- Periodicals; Myelin sheath -- Diseases -- Periodicals; Inflammation -- Periodicals; Multiple sclerosis -- Periodicals; Central Nervous System Diseases -- Periodicals; Demyelinating Diseases -- Periodicals; Inflammation -- Periodicals; Multiple Sclerosis -- Periodicals; Système nerveux central -- Maladies -- Périodiques; Gaine de myéline -- Maladies -- Périodiques; Inflammation (Pathologie) -- Périodiques; Sclérose en plaques -- Périodiques; Electronic journals; 616.834005
• DOI: 10.1177/13524585211054000
• Languages: English
• ISSNs: 1352-4585

Abstract

Background: In a case report of a progressive multiple sclerosis with cerebellar impairments, we reported that synchronisation of steps to beats was possible only at −12% of usual walking cadence during 1 minute of walking. Objectives and methods: Here, we investigate the effect of synchronisation using two different alignment approaches on the patient's gait pattern over 2 minutes of walking, compared to walking in silence. Results and conclusion: This proof of concept showed that the adaptive approach was successful resulting in an improved gait pattern compared to the other conditions, providing preliminary evidence to support a full-scale intervention study.