Somatic symptom count scores do not identify patients with symptoms unexplained by disease: a prospective cohort study of neurology outpatients. Issue 3 (16th June 2014)

• Record Type: Journal Article
• Authors: Carson, Alan J; Stone, Jon; Hansen, Christian Holm; Duncan, Rod; Cavanagh, Jonathon; Matthews, Keith; Murray, G; Sharpe, Michael
• Is Part Of: Journal of neurology, neurosurgery and psychiatry. Volume 86:Issue 3(2015)
• Page Start: 295
• Page End: 301
• Publication Date: 2014-06-16
• Subjects: SOMATISATION DISORDER; Neurology -- Periodicals; Nervous system -- Surgery -- Periodicals; Psychiatry -- Periodicals; 616.8
• DOI: 10.1136/jnnp-2014-308234
• Languages: English
• ISSNs: 0022-3050

Abstract

Abstract : Objective: Somatic symptoms unexplained by disease are common in all medical settings. The process of identifying such patients requires a clinical assessment often supported by clinical tests. Such assessments are time-consuming and expensive. Consequently the observation that such patients tend to report a greater number of symptom has led to the use of self-rated somatic symptom counts as a simpler and cheaper diagnostic aid and proxy measure for epidemiological surveys. However, despite their increasing popularity there is little evidence to support their validity. Methods: We tested the score on a commonly used self-rated symptom questionnaire- the Patient Health Questionnaire (PHQ 15) (plus enhanced iterations including an additional 10 items on specific neurological symptoms and an additional 5 items on mental state) for diagnostic sensitivity and specificity against a medical assessment (with 18 months follow-up) in a prospective cohort study of 3781 newly attending patients at neurology clinics in Scotland, UK. Results: We found 1144/3781 new outpatients had symptoms that were unexplained by disease. The patients with symptoms unexplained by disease reported higher symptoms count scores (PHQ 15: 5.6 (95% CI 5.4 to 5.8) vs 4.2 (4.1 to 4.4) p<0.0001). However, the PHQ15 performed little better than chance in its ability to identify patients with symptoms unexplained by disease. The findings with the enhanced scales were similar. Conclusions: Self-rated symptom count scores should not be used to identify patients with symptoms unexplained by disease.