Pulmonary extramedullary haematopoiesis. (5th December 2011)

• Record Type: Journal Article
• Authors: Mubarak, Veenu; Fanning, Stephen; Windsor, Morgon; Duhig, Edwina; Bowler, Simon
• Is Part Of: BMJ case reports. Volume 2011
• Publication Date: 2011-12-05
• Subjects: Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1136/bcr.06.2011.4392
• Languages: English
• ISSNs: 1757-790X

Abstract

Abstract : A 72-year-old Caucasian lady with myeloproliferative disorder was admitted for evaluation of progressive dyspnoea, weight loss, fatigue and mild hypoxia. A diffuse ground glass opacity was seen on CT pulmonary angiogram. Differential diagnoses included heart failure, infection, progression of myeloproliferative disorder with extramedullary haematopoiesis, thromboembolism or hydroxyurea-induced lung injury. Bronchoscopy and broncho-alveolar lavage were uninformative however lung biopsy with video-assisted thoracoscopy revealed extramedullary haematopoiesis within lung parenchyma. This is a very rare complication of myeloproliferative disorder and the authors discuss the significance of the case, review the literature and report the patient's progress.