Cutaneous absorption of trivalent chromium: tissue levels and treatment by exchange transfusion. Issue 4 (November 1982)

• Record Type: Journal Article
• Authors: Kelly, W F; Ackrill, P; Day, J P; O'Hara, Maureen; Tye, C T; Burton, I; Orton, C; Harris, M
• Is Part Of: Occupational and environmental medicine. Volume 39:Issue 4(1982)
• Page Start: 397
• Page End: 400
• Publication Date: 1982-11
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oem.39.4.397
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : ABSTRACT A man was accidentally immersed in hot acidic trivalent chromium sulphate solution but none was swallowed. The clinical course was dominated by burns, intravascular haemolysis, and acute renal failure. Blood concentrations of chromium were measured during treatment and tissue concentrations were measured at death. Exchange transfusion reduced blood chromium concentrations by two-thirds. The total quantities of chromium absorbed and removed by various routes were calculated. In-vitro studies showed that the chromium solution did not directly cause haemolysis.