Relation between urinary beta-aminoisobutyric acid excretion and concentration of lead in the blood of workers occupationally exposed to lead. Issue 5 (May 1992)

• Record Type: Journal Article
• Authors: Tomokuni, K; Ichiba, M; Mori, K
• Is Part Of: Occupational and environmental medicine. Volume 49:Issue 5(1992)
• Page Start: 365
• Page End: 368
• Publication Date: 1992-05
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oem.49.5.365
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : Urinary beta-aminoisobutyric acid (ABA) concentration was determined by fluorometric high performance liquid chromatography in 22 workers occupationally exposed to lead. The urinary excretion of ABA was increased with increasing exposure to lead. The excretion of urinary ABA had a significant correlation with concentration of lead in blood (Pb-B) (r = 0.581), similar to the correlation of Pb-B with urinary delta-aminolaevulinic acid (ALA) concentration (r = 0.563). The determination of urinary ABA concentration in workers exposed to lead, therefore, may offer a new approach for evaluating the health effect of lead.