0431 The contribution of molecular epidemiology to studying occupational disease: some accomplishments to date and opportunities for the future. (23rd June 2014)

• Record Type: Journal Article
• Authors: Rothman, Nat; Vermeulen, Roel; Lan, Qing
• Is Part Of: Occupational and environmental medicine. Volume 71(2014)Supplement 1
• Page Start: A124
• Page End: A124
• Publication Date: 2014-06-23
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oemed-2014-102362.391
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : Objectives: There are several contributions that molecular epidemiology can make to the study of occupational disease. Method: These include 1) enhancing the ability to study dose-response relationships; 2) evaluating the biological plausibility that an exposure may be related to an adverse outcome; and 3) providing insight into the underlying biological mechanism of an established or suspected exposure-disease relationship. These goals can overlap at times. Results: There are multiple examples where molecular epidemiology studies have contributed important information about occupational exposures, including instances where such studies contributed data that played a role in determining if a given exposure was causally related to disease. Historically, these studies have complimented classic epidemiological investigations. Conclusions: There are multiple examples where molecular epidemiology studies have contributed important information about occupational exposures, including instances where such studies contributed data that played a role in determining if a given exposure was causally related to disease. Historically, these studies have complimented classic epidemiological investigations.