An extension of nickel-catalyzed reductive coupling between tertiary alkyl halides with allylic carbonates. Issue 39 (27th September 2018)

• Record Type: Journal Article
• Authors: Yu, Yingying; Chen, Haifeng; Qian, Qun; Yao, Ken; Gong, Hegui
• Is Part Of: Tetrahedron. Volume 74:Issue 39(2018)
• Page Start: 5651
• Page End: 5658
• Publication Date: 2018-09-27
• Subjects: Allylation -- Chloro-cyclotryptamine -- Nickel catalyzed -- Extension -- Dienyl carbonate; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tet.2018.07.057
• Languages: English
• ISSNs: 0040-4020

Abstract

Abstract: The nickel catalyzed reductive coupling of allylic carbonates with chloro-cyclotryptamine analogs to construct sterically congested all C(sp 3 ) quaternary centers has been achieved with emphasis on the substrate scope. And the using of dienyl methyleneyl carbonates coupling with a variety of tertiary alkyl halides furnished the dienylated products improved the reaction's applicability. Graphical abstract: Image 1