Effects of dietary Macleaya cordata extract on growth performance, immune responses, antioxidant capacity, and intestinal development in weaned piglets. Issue 1 (1st January 2019)

• Record Type: Journal Article
• Authors: Chen, Jiashun; Kang, Baoju; Yao, Kang; Fu, Chenxing; Zhao, Yurong
• Is Part Of: Journal of applied animal research. Volume 47:Issue 1(2019)
• Page Start: 349
• Page End: 356
• Publication Date: 2019-01-01
• Subjects: Macleaya cordata extract -- growth performance -- immune responses -- antioxidant capacity -- intestinal development -- weaned piglets; Animal culture -- India -- Periodicals; Animal culture -- Tropics -- Periodicals; 636.005
• DOI: 10.1080/09712119.2019.1636800
• Languages: English
• ISSNs: 0971-2119

Abstract

ABSTRACT: This study was conducted to investigate the effects of Macleaya cordata extract (MCE) on growth performance, immune responses, antioxidant capacity, intestinal morphology and microbiota in weaned piglets. A total of 36 weaned piglets [Duroc× (Large White × Landrace)] with an average body weight of 6.55 ± 0.32 kg at weaning were used in a 21-day experiment. Pigs were divided into three treatments ( n = 12). Control (basal diet); MCE (basal diet plus MCE) and ABO (basal diet plus 20 mg/kg falvomycin & 100 mg/kg aureomycin). Compared with the control group, piglets in the MCE and ABO groups had higher average daily gain, lower feed efficiency and diarrhea rates ( P < 0.05). Serum IgG level in MCE -fed piglets was higher ( P < 0.05) than that of control -fed piglets. A higher ( P < 0.05) serum the activity of total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD) was observed in MCE-fed piglets than those in the control and ABO groups. The addition of MCE increased the amount of Lactobacillus spp . ( P < 0.05), while decreased the amount of Salmonella spp . ( P < 0.05) and tended to reduce the E. coli population ( P < 0.10). Dietary MCE increased villus height and the villus height to crypt depth ratio in the duodenum, jejunum and ileum, and decreased the crypt depth in the jejunum of piglets ( P < 0.05). In conclusion, dietary MCE supplementation would exert beneficial effects on growth performance, immune status, antioxidant capacity and the intestinal health and may be used as a potential alternative to antibiotics in weaned piglets.