Cover Feature: Time‐Dependent Cytotoxic Properties of Terpyridine‐Based Copper Complexes (ChemBioChem 16/2020). (20th July 2020)

• Record Type: Journal Article
• Authors: Grau, Jordi; Caubet, Amparo; Roubeau, Olivier; Montpeyó, David; Lorenzo, Julia; Gamez, Patrick
• Is Part Of: Chembiochem. Volume 21:Number 16(2020)
• Page Start: 2227
• Page End: 2227
• Publication Date: 2020-07-20
• Subjects: antineoplastic agents -- cell death -- chemical nuclease -- copper -- oxidative cleavage; Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.202000481
• Languages: English
• ISSNs: 1439-4227

Abstract

Abstract : The cover feature picture shows the progressive activation of terpyridine‐based copper(II) compounds that are not cytotoxic against various cell lines after 24 h of incubation but become highly efficient after 72 h of incubation, with IC50 values in the low‐micromolar to nanomolar range. More information can be found in the full paper by A. Caubet, P. Gamez, et al.