Recombinant erythropoietin in clinical practice. Issue 933 (1st July 2003)

• Record Type: Journal Article
• Authors: Ng, T; Marx, G; Littlewood, T; Macdougall, I
• Is Part Of: Postgraduate medical journal. Volume 79:Issue 933(2003)
• Page Start: 367
• Page End: 376
• Publication Date: 2003-07-01
• Subjects: recombinant erythropoietin -- anaemia -- clinical applications; G-CSF, granulocyte colony-stimulating factor -- NESP, novel erythropoiesis stimulating protein -- PRCA, pure red cell aplasia -- RBCs, red blood cells -- RHuEPO, recombinant human erythropoietin Please note that packed cell volume is used in the text -- this is equivalent to haematocrit; Medicine -- Periodicals; 610
• DOI: 10.1136/pmj.79.933.367
• Languages: English
• ISSNs: 0032-5473

Abstract

Abstract : The introduction of recombinant human erythropoietin (RHuEPO) has revolutionised the treatment of patients with anaemia of chronic renal disease. Clinical studies have demonstrated that RHuEPO is also useful in various non-uraemic conditions including haematological and oncological disorders, prematurity, HIV infection, and perioperative therapies. Besides highlighting both the historical and functional aspects of RHuEPO, this review discusses the applications of RHuEPO in clinical practice and the potential problems of RHuEPO treatment.