A genetic linkage study of a kindred with X-linked retinitis pigmentosa. Issue 5 (May 1985)

• Record Type: Journal Article
• Authors: Bhattacharya, S S; Clayton, J F; Harper, P S; Hoare, G W; Jay, M R; Lyness, A L; Wright, A F
• Is Part Of: British journal of ophthalmology. Volume 69:Issue 5(1985)
• Page Start: 340
• Page End: 347
• Publication Date: 1985-05
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjo.69.5.340
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : A large kindred with X-linked retinitis pigmentosa (XLRP) was investigated clinically and by means of genetic linkage with a view to developing methods of carrier detection and early diagnosis. A restriction fragment length polymorphism, identified by recombinant DNA probe L1.28, showed close genetic linkage to XLRP in this kindred and is a potentially useful marker for the purposes of genetic counselling.