Malignant progression of laryngeal papilloma associated with human papilloma virus type 6 (HPV-6) DNA. Issue 3 (March 1988)

• Record Type: Journal Article
• Authors: Zarod, A P; Rutherford, J D; Corbitt, G
• Is Part Of: Journal of clinical pathology. Volume 41:Issue 3(1988)
• Page Start: 280
• Page End: 283
• Publication Date: 1988-03
• Subjects: Pathology -- Periodicals; Pathology, Molecular -- Periodicals; 616.0705
• DOI: 10.1136/jcp.41.3.280
• Languages: English
• ISSNs: 0021-9746

Abstract

Abstract : A case of laryngeal squamous papilloma in the early stages of development showed histological features suggestive of virus infection. Five years later positive evidence of HPV-6 infection was obtained at a time when the lesion had developed into a squamous cell carcinoma. It is concluded that this case represents a complete example of the virus to papilloma to carcinoma sequence, and as far as is known, is the first reported case of its kind in the larynx.