The efficacy and safety of posterior scleral reinforcement using genipin cross-linked sclera for macular detachment and retinoschisis in highly myopic eyes. Issue 11 (25th February 2016)

• Record Type: Journal Article
• Authors: Zhu, Shuang-Qian; Zheng, Lin-Yan; Pan, An-Peng; Yu, A-Yong; Wang, Qin-Mei; Xue, An-Quan
• Is Part Of: British journal of ophthalmology. Volume 100:Issue 11(2016)
• Page Start: 1470
• Page End: 1475
• Publication Date: 2016-02-25
• Subjects: Retina -- Treatment Surgery -- Macula; Ophthalmology -- Periodicals; 617.7
• DOI: 10.1136/bjophthalmol-2015-308087
• Languages: English
• ISSNs: 0007-1161

Abstract

Abstract : Background/aims: To evaluate the efficacy and safety of posterior scleral reinforcement (PSR) using genipin cross-linked sclera as the material to treat macular detachment and retinoschisis, both without macular hole, in highly myopic eyes. Methods: Twenty-one patients with highly myopic eyes (24 eyes) with macular detachment and retinoschisis were treated sequentially with genipin cross-linked PSR and were followed for at least 1 year after surgery. The best-corrected visual acuity (BCVA), spherical equivalent (SE) power, axial length (AL), optical coherence tomography, and the complications were evaluated. Results: The mean SE decreased from −13.81±4.67 D preoperatively to −9.64±4.86 D postoperatively, while the improvement in the logMAR BCVA values was from 1.24±0.57 before surgery to 1.03±0.57 after surgery. The preoperative AL (29.73±2.31 mm) was decreased (28.08±2.08 mm) after the operation. The retina in 21 eyes (87.5%) was successful reattached and the macular detachment was significantly decreased in two eyes; a macular hole occurred in one eye. Conclusions: For at least a 1 year period of follow-up, PSR with genipin cross-linked sclera was safe and effective to treat macular detachment and retinoschisis in high myopia when a macular hole was not present. The reinforcement effect tended to be stabilised and maintained for 6 months after treatment.