P052 Identifying environmental hazardous substances associated with prostate cancer risk in hong kong population. (1st September 2016)

• Record Type: Journal Article
• Authors: Tse, Lap Ah; Ng, Chi Fai; Ho, Wing Ming; Lee, Ming Yi Priscilla; Wang, Feng
• Is Part Of: Occupational and environmental medicine. Volume 73(2016)Supplement 1
• Page Start: A138
• Page End: A138
• Publication Date: 2016-09-01
• Subjects: Medicine, Industrial -- Periodicals; Environmental health -- Periodicals; 616.980305
• DOI: 10.1136/oemed-2016-103951.375
• Languages: English
• ISSNs: 1351-0711

Abstract

Abstract : Objective: To identify environmental hazardous substances those are potentially related to the risk of prostate cancer among Hong Kong men. Methods: This is an ongoing case-control study. We are targeting to obtain a total of 400 incident prostate cancer cases and 400 frequency age-matched controls that were consecutively recruited from one public hospital in Hong Kong. Using a standardised questionnaire, we obtained each participant's socio-demographics, diet and other lifestyle habits, occupational exposures, family cancer histories, and environmental exposure to Bisphenol A Exposure (BPA). Information on BPA exposure of each subject was obtained by collecting the habits of using food and water containers. Results: By November 2015, a total of 360 confirmed prostate cancer incidence cases and 159 hospital controls were recruited and analysed. Compared with the controls, prostate cancer cases had a higher proportion of alcohol drinking (21.4% vs 15.7%) and night shift work (14.9% vs. 6.0%), but they had a relatively low proportion of colleague education or above (12.9% vs. 15.0%). More prostate cancer cases came from poor family (i.e., monthly family income less than USD 516) than the controls (40.1% vs. 29.8%). Based on the current dataset, we did not observe an obvious difference in smoking prevalence and BPA exposure among cases and controls. Conclusion: Our ongoing study identified that alcohol drinking, night shift work, and low socioeconomic status are the potential environmental hazardous factors for the risk of prostate cancer; however, these findings will be updated in the EPICOH2016. Acknowledgement: Health and Medical Research Fund (HMRF), Project No.: 11121091; correspondence: [e-mail]