Water and electrolyte absorption by the colon in tropical sprue. Issue 10 (October 1982)

• Record Type: Journal Article
• Authors: Ramakrishna, B S; Mathan, V I
• Is Part Of: Gut. Volume 23:Issue 10(1982)
• Page Start: 843
• Page End: 846
• Publication Date: 1982-10
• Subjects: Gastroenterology -- Periodicals; 616.33
• DOI: 10.1136/gut.23.10.843
• Languages: English
• ISSNs: 0017-5749

Abstract

Abstract : A defect in colonic absorption of electrolytes and water was demonstrated in patients with tropical sprue by perfusing the colon with normal saline containing a non-absorbable marker. Colonic water absorption correlated negatively with stool weight and was abnormal in patients with steatorrhoea. The possible mechanisms producing this defect are discussed. This defect may be related to colonocyte damage produced by unabsorbed unsaturated fatty acids in patients with steatorrhoea.