Abnormal expression of glucose-6-phosphatase in preterm infants. Issue 2 (February 1993)

• Record Type: Journal Article
• Authors: Hume, R; Burchell, A
• Is Part Of: Archives of disease in childhood. Volume 68:Issue 2(1993)
• Page Start: 202
• Page End: 204
• Publication Date: 1993-02
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.68.2.202
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : The hepatic microsomal glucose-6-phosphatase enzyme was studied in liver samples from 76 premature infants including 15 victims of sudden infant death syndrome. The data obtained were compared with glucose-6-phosphatase activity in liver samples from 95 term infants. In the majority of preterm infants up to 350 days of age the activity of the glucose-6-phosphatase enzyme was at or below the extreme low limit of the normal range in term infants. The premature infants with the lowest hepatic microsomal glucose-6-phosphatase activities are likely to be at risk of hypoglycaemic episodes during periods of relative starvation or stress.