Partial splenectomy in cystic fibrosis patients with hypersplenism. Issue 2 (1st February 2003)

• Record Type: Journal Article
• Authors: Thalhammer, G H; Eber, E; Uranüs, S; Pfeifer, J; Zach, M S
• Is Part Of: Archives of disease in childhood. Volume 88:Issue 2(2003)
• Page Start: 143
• Page End: 146
• Publication Date: 2003-02-01
• Subjects: cystic fibrosis -- partial splenectomy -- portal hypertension -- splenomegaly; Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.88.2.143
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : We report three cystic fibrosis (CF) patients with hypersplenism who underwent partial splenectomy. The postoperative course was uneventful in two patients; one patient developed a complication necessitating resection of the rest of the spleen. Haematological parameters improved and oesophageal varices regressed in all patients. On follow up, one patient showed a normal spleen, the other a normally functioning accessory spleen; the third patient again developed splenomegaly with hypersplenism. Partial splenectomy is a promising therapeutic option for CF patients with hypersplenism.