Pediatric Inflammatory Multisystem Syndrome With Central Nervous System Involvement and Hypocomplementemia Following SARS-COV-2 Infection. Issue 8 (August 2020)

• Record Type: Journal Article
• Authors: Regev, Tslil; Antebi, Maayan; Eytan, Danny; Shachor-Meyouhas, Yael; Ilivitzki, Anat; Aviel, Yonatan Butbul; Ben-Ari, Josef
• Is Part Of: Pediatric infectious disease journal. Volume 39:Issue 8(2020)
• Publication Date: 2020-08
• Subjects: Communicable diseases in children -- Periodicals; Infection in children -- Periodicals; 618.929
• DOI: 10.1097/INF.0000000000002804
• Languages: English
• ISSNs: 0891-3668

Abstract

Abstract : Pediatric inflammatory multisystem syndromes associated with Severe Acute Respiratory Syndrome Coronavirus 2 are emerging in recent reports. We describe a patient with critical illness consistent with atypical Kawasaki disease with cardiac dysfunction and abdominal involvement presenting weeks after Severe Acute Respiratory Syndrome Coronavirus 2 infection. Our patient showed unique central nervous system involvement with small vessel vasculitis and profound hypocomplementemia, both not previously reported in case descriptions and may hint at possible disease mechanisms.