Antineutrophil cytoplasm antibodies in Kawasaki disease. Issue 3 (March 1989)

• Record Type: Journal Article
• Authors: Savage, C O; Tizard, J; Jayne, D; Lockwood, C M; Dillon, M J
• Is Part Of: Archives of disease in childhood. Volume 64:Issue 3(1989)
• Page Start: 360
• Page End: 363
• Publication Date: 1989-03
• Subjects: Children -- Diseases -- Periodicals; Infants -- Diseases -- Periodicals; 618.920005
• DOI: 10.1136/adc.64.3.360
• Languages: English
• ISSNs: 0003-9888

Abstract

Abstract : Autoantibodies against components of neutrophil cytoplasm develop during adult vasculitic diseases such as Wegener's granulomatosis and microscopic polyarteritis, and they are predominantly of the IgG class. Similar but distinct antibodies have been described in children with Kawasaki disease and both IgM and IgG class antibodies are represented. This adds another clinically distinct childhood form of vasculitis to the adult forms in which autoantibodies to neutrophil cytoplasmic antigens have been detected.