A haunted beast: Targeting STAT5BN642H in T-Cell Neoplasia. (4th May 2018)
- Record Type:
- Journal Article
- Title:
- A haunted beast: Targeting STAT5BN642H in T-Cell Neoplasia. (4th May 2018)
- Main Title:
- A haunted beast: Targeting STAT5BN642H in T-Cell Neoplasia
- Authors:
- Pham, Ha Thi Thanh
Hengstschläger, Markus
Moriggl, Richard - Abstract:
- ABSTRACT: The somatic hot spot mutation STAT5BN642H was found in many T cell leukemia/lymphoma patients. We generated and analyzed a transgenic mouse model with hematopoietic STAT5BN642H expression that caused aggressive T-cell leukemia/lymphomas. Herein, we discuss the scientific merit of our model and its relevance for pre-clinical studies.
- Is Part Of:
- Molecular & cellular oncology. Volume 5:Number 3(2018)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 5:Number 3(2018)
- Issue Display:
- Volume 5, Issue 3 (2018)
- Year:
- 2018
- Volume:
- 5
- Issue:
- 3
- Issue Sort Value:
- 2018-0005-0003-0000
- Page Start:
- Page End:
- Publication Date:
- 2018-05-04
- Subjects:
- Aurora kinase -- JAK kinase -- STAT5 N642H driver mutation -- T-cell neoplasia
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2018.1435181 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 19104.xml