The important role of polysaccharides from a traditional Chinese medicine-Lung Cleansing and Detoxifying Decoction against the COVID-19 pandemic. (15th July 2020)

• Record Type: Journal Article
• Authors: Cao, Peng; Wu, Sanlan; Wu, Tingting; Deng, Yahui; Zhang, Qilin; Wang, Kaiping; Zhang, Yu
• Is Part Of: Carbohydrate polymers. Volume 240(2020)
• Publication Date: 2020-07-15
• Subjects: COVID-19 -- Coronavirus -- Polysaccharide -- Lung Cleansing and Detoxifying Decoction -- Qing Fei Pai Du Tang -- Traditional Chinese Medicine; Polysaccharides -- Periodicals; Polysaccharides -- Periodicals; Polysaccharides -- Périodiques; Electronic journals; 547.78
• DOI: 10.1016/j.carbpol.2020.116346
• Languages: English
• ISSNs: 0144-8617

Abstract

Highlights: COVID-19 has become a Public Health Emergency of International Concern (PHEIC) and a world-wide pandemic. The Lung Cleansing and Detoxifying Decoction has shown definite therapeutic effects on COVID-19 patients. Water-soluble polysaccharides in Lung Cleansing and Detoxifying Decoction possess multiple bioactivities. Producing COVID-19 vaccines with polysaccharides as the adjuvants is an innovative strategy. Abstract: The new coronavirus pneumonia, named COVID-19 by the World Health Organization, has become a pandemic. It is highly pathogenic and reproduces quickly. There are currently no specific drugs to prevent the reproduction and spread of COVID-19. Some traditional Chinese medicines, especially the Lung Cleansing and Detoxifying Decoction (Qing Fei Pai Du Tang), have shown therapeutic effects on mild and ordinary COVID-19 patients. Polysaccharides are important ingredients in this decoction. This review summarizes the potential pharmacological activities of polysaccharides isolated by hot water extraction from Lung Cleansing and Detoxifying Decoction, which is consistent with its production method, to provide the theoretical basis for ongoing research on its application.