A direct role of RNA polymerase III and RNA in DNA homologous recombination. (4th July 2021)
- Record Type:
- Journal Article
- Title:
- A direct role of RNA polymerase III and RNA in DNA homologous recombination. (4th July 2021)
- Main Title:
- A direct role of RNA polymerase III and RNA in DNA homologous recombination
- Authors:
- Liu, Sijie
Kong, Daochun - Abstract:
- ABSTRACT: End resection excises several thousand bases from the 5ʹ-ended strand during DNA double-strand break repair, creating 3ʹ-end single-stranded DNA overhangs. This overhang requires strict protection from DNA2 or other nucleases digestion. A recent finding showed that the 3ʹ-end overhangs are protected by the transient formation of RNA-DNA hybrids, and RNA polymerase III is an essential factor for homologous recombination.
- Is Part Of:
- Molecular & cellular oncology. Volume 8:Number 4(2021)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 8:Number 4(2021)
- Issue Display:
- Volume 8, Issue 4 (2021)
- Year:
- 2021
- Volume:
- 8
- Issue:
- 4
- Issue Sort Value:
- 2021-0008-0004-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-07-04
- Subjects:
- DNA double-strand breaks -- genetic deletion -- homologous recombination -- RNA–DNA hybrids -- RNA polymerase III
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2021.1935173 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 19106.xml