Regulation of glycolysis and cancer cell proliferation by PKM2 citrullination. (4th July 2021)
- Record Type:
- Journal Article
- Title:
- Regulation of glycolysis and cancer cell proliferation by PKM2 citrullination. (4th July 2021)
- Main Title:
- Regulation of glycolysis and cancer cell proliferation by PKM2 citrullination
- Authors:
- Coassolo, Sébastien
Davidson, Irwin - Abstract:
- ABSTRACT: Conversion of peptidyl-arginine to peptidyl citrulline, known as citrullination, is a post-translational protein modification catalyzed by the PADI (Protein Arginine Deiminase) family of enzymes. PADI1 and PADI3 catalyze citrullination of arginine 106 in the glycolytic enzyme pyruvate kinase M2 modulating its allosteric regulation, glycolysis and cancer cell proliferation.
- Is Part Of:
- Molecular & cellular oncology. Volume 8:Number 4(2021)
- Journal:
- Molecular & cellular oncology
- Issue:
- Volume 8:Number 4(2021)
- Issue Display:
- Volume 8, Issue 4 (2021)
- Year:
- 2021
- Volume:
- 8
- Issue:
- 4
- Issue Sort Value:
- 2021-0008-0004-0000
- Page Start:
- Page End:
- Publication Date:
- 2021-07-04
- Subjects:
- NuRD complex -- chromatin -- melanoma -- protein arginine deiminase -- allosteric regulation
Tumors -- Periodicals
Neoplasms
Periodicals
616.99 - Journal URLs:
- http://www.tandfonline.com/loi/kmco20#.VyIIeFL2aic ↗
http://www.tandfonline.com/ ↗ - DOI:
- 10.1080/23723556.2021.1927446 ↗
- Languages:
- English
- ISSNs:
- 2372-3556
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 19106.xml