Acute respiratory distress in diabetic ketoacidosis: possible contribution of low colloid osmotic pressure. Issue 6367 (5th March 1983)

• Record Type: Journal Article
• Authors: Leonard, R C; Asplin, C; McCormick, C V; Hockaday, T D
• Is Part Of: BMJ. Volume 286:Issue 6367(1983)
• Page Start: 760
• Page End: 762
• Publication Date: 1983-03-05
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.286.6367.760
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : The "shock lung" syndrome may occur in diabetic ketoacidosis in association with disseminated intravascular coagulation; occasionally it occurs alone after treatment of the ketoacidosis. Two patients developed pulmonary opacities with clinical features of acute respiratory distress such as are seen in the shock lung syndrome; in both, however, the findings suggested a different mechanism from that occurring in the syndrome. Hypoalbuminaemia was prominent, and it is postulated that a low plasma osmotic pressure caused by high volume crystalloid infusions may have precipitated the acute respiratory complications. Plasma osmotic pressure may be an important variable in patients given large volumes of crystalloid infusions; further studies are required to elucidate mechanisms of pulmonary oedema in such patients.