Younger Age of Presentation and Extraosseous Tumour in IgD Myelomatosis. Issue 5641 (15th February 1969)

• Record Type: Journal Article
• Authors: Hobbs, J. R.; Corbett, A. A.
• Is Part Of: BMJ. Volume 1:Issue 5641(1969)
• Page Start: 412
• Page End: 414
• Publication Date: 1969-02-15
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610
• DOI: 10.1136/bmj.1.5641.412
• Languages: English
• ISSNs: 0007-1447

Abstract

Abstract : A study of 14 personal patients and 16 others in the literature shows that (1) IgD myelomatosis often presents at a significantly younger age than other forms of myelomatosis, and (2) during life extraosseous tumour can be detected in about two-thirds of these patients. The IgD form represents 1·5% of myelomatosis and shows an increased incidence of osteolytic lesions, hypercalcaemia, and renal failure, together with heavy Bence Jones proteinuria (90% type L). Like only Bence Jones myelomatosis, the IgD form seems to behave clinically in a more vicious manner.